sampleprep_logo
CG-500-1
CG-500-2
CG-500-3
CG-500-4
CG-500-1
CG-500-2
CG-500-3
CG-500-4

Cole-Parmer® SamplePrep CG-500 Freezer/Mill® Dual-Chamber Cryogenic Grinder


Part Number: 6875D

The CG-500 Freezer/Mill® is designed for labs that need fast, reliable cryogenic grinding for large or multiple samples. This high-throughput dual chamber laboratory mill quickly cools and pulverizes tough materials into a fine powder without thermal degradation or cross-contamination. The unit accommodates samples in the 0.1 to 100-gram range (50 gram per grinding chamber).

Typical applications include: DNA/RNA extraction, forensic/drug testing, RoHS/WEEE, consumer product testing, food safety, materials research, and medical research.

Typical samples include: animal tissue, plastic and polymers, yeast, pharmaceuticals, food products, electronic components, textiles, hair, teeth, bones, plant tissue such as cannabis, seeds, leaves and roots.

Before and After - Bottle Caps
Bottle-Caps.jpg

  • Reach cryogenic temperatures in minutes.
  • Equipped with liquid nitrogen (LN) level sensor that shuts shuts down the mill if LN level is too low. Liquid nitrogen required for operation.
  • Lid safety interlock for operator protection prevents mill from running if lid is not latched shut.
  • Grinds samples in the 0.1-100 gram range (50 gram per chamber). Each grinding chamber can hold one large grinding vial, one mid-size vial, four standard grinding vials or four microvial sets
  • Touchscreen stores up to 20 user-defined grinding programs for quick and easy recall, includes run history, training videos, and manuals.
  • Additional pre-cooling chmabers to increase sample throughput.
  • Maintenance-free design with only one moving part.
  • 1 year warranty.


The Cole-Parmer SamplePrep CG-500 Freezer/Mill processes samples faster with the dual grinding chamber that handles up to 50 grams of sample per chamber. Each chamber holds a variety of vial sizes from large grinding vials to microvial sets. The unit includes two additional pre-cooling chambers for increased efficiency.

Continuous liquid nitrogen immersion maintains cryogenic temperatures ensuring temperature-sensitive samples remain stable, preserving sample integrity. Sealed vials prevent contamination, protecting hazardous or critical materials.

Advanced autofill liquid nitrogen system eliminates manual refilling if liquid nitrogen for effortless operation. The manual fill option is available for labs that prefer hands-on control. Proved dual electromagnetic grinding technology ensures fast and effective pulverization.

The CG-500 Freezer/Mill is built for safety and reliability. The enhanced safety features of the Cole-Parmer SamplePrep Freezer/Mill include a lid interlock system that stops the grinding process if the lid is opened mid-process. The liquid nitrogen sensor automatically shuts down the unit if liquid nitrogen levels are too low, preventing overheating. Please note, the mill must be used in an open, well-ventilated area to avoid condensation-related damage. Protective gear including cryogenic gloves and a face shield is recommended when handling liquid nitrogen.

Purchase liquid nitrogen, extractor and sample vials separately.

Model Number CG-500
Type of Mill Dual chamber cryogenic impact mill
Grinding Vials One large vial (6801, 6803, 6871), one mid-size vial (6881, 6883,
6885), one to four small vials (6751, 6761, 6771, 6781S) or one to
four microvial sets (6757). (Per Chamber)
Typical Vial Capacity Small Vial: actual volume with impactor, approx. 25 ml. Typical sample weights: 2 grams for biological samples, 1 gram for polymers.

Microvial Set: 100 - 500 mg per individual Microvial, depending on sample.

Mid-Size Vial: up to 5 times the sample capacity of Small Vial.

Large Vial: Approximately twice the sample capacity of Mid-Size Vial, or up to 10 times that of Small Vial.

Actual performance of any vial/sample combination depends on sample properties, cooling time, grinding time, desired outcome, etc. Effective capacity for a given sample is determined by experiment. Overfilling a vial greatly reduces its efficiency. 
Display Touchscreen
Grinding Mechanism Steel impactor driven by magnetic coil
Data Transfer Dual USB ports (back of controller)
Coolant Liquid nitrogen (LN)

Typical liquid nitrogen volume needed is 15-19 liters for initial cool-down and filling of the tub. Liquid nitrogen consumption is 4-6 liters for each hour or operation.

Actual liquid nitrogen consumption can vary. A minimum 200 liter LN tank is recommended.
   
Voltage 115 V/60 Hz or 230 V/50 Hz
Power Cord 115 V/60 Hz model: 3-prong grounded plug supplied
230 V/50 Hz model: 2-prong European plug supplied
Dimensions (L x W x H) 50.8 x 55.0 x 64.8 cm (20.0 x 21.5 x 25.5 in.)
Net Weight 35.4 kg (78 lb) empty, without vial or coolant
CE Approved Yes
Warranty 1 year

© Cole-Parmer All Rights Reserved