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Cole-Parmer® SamplePrep HG-400 MiniG® Tissue Homogenizer and Cell Lyser


Part Number: 1600

The HG-400 MiniG® is the perfect solution for labs looking for a compact yet high-performance tissue homogenizer and cell lyser. Designed for quick and efficient sample processing, this versatile system ensures fast and consistent extractions of nucleic acids, proteins, and other key molecules—all with minimal effort. It is equipped with an adjustable clamp that accommodates a full range of sample vials from 2 mL to 50 mL centrifuge tubes or up to two deep-well titer plates. It is specifically designed for rapid cell disruption, cell lysis and tissue homogenization through bead beating.

Typical applications include: tissue homogenization, DNA/RNA research and extraction, cell lysis, protein extraction, biofuel research, pesticide residue extraction using QuEChERS or the SweEt method.

Typical samples include: animal tissue, plant tissue, cell cultures, fruit, cannabis, seeds, yeast and bacteria.

Before and After - Corn
Corn.jpg

  • Mechanical disruption through bead beating, ideal for high-throughput cell lysis applications including DNA/ RNA extraction, protein extraction and pesticide residue analysis.
  • Window in lid allows you to see the grinding process.
  • Comes with an adjustable clamp that allows users to secure vials or titer plates of various sizes.
  • Lid has a safety interlock switch that stops the motor if the lid is opened during the grinding process.
  • Optional Kryo-Tech® Accessories enable cryogenic grinding and preserve temperature sensitive samples for RNA and protein extractions.
  • LCD display screen shows run times in minute:second format.
  • Rate & timer controls allow you to adjust speed and set time.
  • Start and stop buttons allow you to start and stop the grinding process.
  • 1 year warranty.
 

The Cole-Parmer SamplePrep HG-400 MiniG® is designed for fast, reliable and efficient sample processing. The unit homogenizes cells and tissues in less than two minutes with powerful bead beating technology. The HG-400 works with a variety of sample types including seeds, stems, roots, leaves, and animal tissue.

The MiniG accommodates 2 mL to 50 mL centrifuge tubes or up to two deep-well titer plates. The adjustable clamp secures different vial sizes, ensuring flexibility for various applications. The easy to operate unit lets you load samples, set time and speed, and press start, and let the MiniG do the work.

Reliable and consistent results through the mechanical grinding process that eliminates the variability of manual grinding, making it ideal for high-throughput labs. The HG-400 MiniG works with or without buffer allowing for dry pulverization of plant tissue using grinding balls.

The vertical shaking motion delivers strong and uniform disruption. Its small footprint makes is easy to optimize lab space without sacrificing performance.

Model Number HG-600
Type of Mill Bead beater, homogenizer
Capacity Maximum sample load 0.54 kg (1.2 lb)

NOTE: Operating with loads that exceed the recommended maximum weight limits can result in damage to the HG-400 MiniG®. Therefore, warranty restrictions or invalidation may apply.
Display Touchscreen
Grinding Mechanism Grinding balls of stainless steel, ceramic or plastic balls
Motor 1/7 HP, maximum speed 1516 rpm
Fuse 3AG 8-amp, 250 V slow-blow fuse
Clamp Speed Variable: 500 to 1500 strokes/minute
Clamp Travel 3.2 cm (1.25 in.)
Run Timer Maximum 10 minutes, digital display in minutes:seconds
Voltage 115 V/230 V, 60/50 Hz
Power Cord 115 V/60 Hz model: 3-prong grounded plug supplied
230 V/50 Hz model: 2-prong European plug supplied
Dimensions (H x W x D) 54.6 x 28.6 x 43.2 cm (21.5 x 11.25 x 17.0 in.)
Net Weight 11 kg (49 lb)
Operating Conditions For indoor use only at a maximum altitude of 2000 m (6600 ft). Operate at ambient conditions between 5 ºC and 40 ºC (40 °F and 104 ºF) with maximum relative humidity 80% below 31 ºC (88°F). Pollution degree 1: none or only dry, conductive pollution occurs.
CE Approved Yes
Warranty 1 year